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主要文件

安全信息

SAB5700684

Sigma-Aldrich

Anti-TLR4 antibody produced in rabbit

别名:

ARMD10, CD284, TLR-4, TLR4, TOLL

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选择尺寸

2 ML
¥4,638.25

¥4,638.25


预计发货时间2025年5月16日详情



选择尺寸

变更视图
2 ML
¥4,638.25

About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

¥4,638.25


预计发货时间2025年5月16日详情


生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

73
91
95

种属反应性

mouse, human, rat

浓度

0.94 mg/ml

技术

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

一般描述

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TLR4 (NP_612564.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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