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SAB5700016

Anti-PARP1 antibody produced in rabbit

Name: Anti-PARP1 antibody produced in rabbit
Brand: SIGMA

别名:

ADPRT, ADPRT 1, ADPRT1, ARTD1, Cleaved PARP, PARP, PARP-1, PARP1, PPOL, pADPRT-1

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ChIP, IF, IHC, IP, WB

Citations:

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属性

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

113

species reactivity

rat, human, mouse

concentration

2.78 mg/ml

technique(s)

ChIP: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200, immunoprecipitation (IP): 1:50-1:200, western blot: 1:1000-1:3000

UniProt accession no.

P09874

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PARP1(142)

说明

General description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c