推荐产品
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
2C8, monoclonal
分子量
36 kDa
种属反应性
human
技术
direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000
同位素/亚型
IgG2b
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PBK(55872)
相关类别
免疫原
Purified recombinant fragment of human PBK expressed in E.coli.
Mouse monoclonal antibody raised against PBK
Mouse monoclonal antibody raised against PBK
外形
Ascitic fluid containing 0.03% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Giacomo Pirovano et al.
Molecular imaging and biology, 21(4), 705-712 (2018-10-26)
Lymphokine-activated killer T cell-originated protein kinase (TOPK) is a fairly new cancer biomarker with great potential for clinical applications. The labeling of a TOPK inhibitor with F-18 can be exploited for positron emission tomography (PET) imaging allowing more accurate patient
Giacomo Pirovano et al.
British journal of cancer, 117(4), 503-512 (2017-07-06)
Tumour-specific radiosensitising treatments may enhance the efficacy of radiotherapy without exacerbating side effects. In this study we determined the radiation response following depletion or inhibition of TOPK, a mitogen-activated protein kinase kinase family Ser/Thr protein kinase that is upregulated in
Giacomo Pirovano et al.
European journal of nuclear medicine and molecular imaging, 47(4), 1003-1010 (2019-11-18)
OTS514 is a highly specific inhibitor targeting lymphokine-activated killer T cell-originated protein kinase (TOPK). A fluorescently labeled TOPK inhibitor could be used for tumor delineation or intraoperative imaging, potentially improving patient care. Fluorescently labeled OTS514 was obtained by conjugating the
Katharine J Herbert et al.
Cell death and differentiation, 28(4), 1333-1346 (2020-11-11)
T-LAK-originated protein kinase (TOPK) overexpression is a feature of multiple cancers, yet is absent from most phenotypically normal tissues. As such, TOPK expression profiling and the development of TOPK-targeting pharmaceutical agents have raised hopes for its future potential in the
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