Monoclonal Anti-beta 4 Spectrin-Horseradish Peroxidase antibody produced in mouse

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Derived from animal serum

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

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