偶联物
unconjugated
质量水平
抗体产品类型
primary antibodies
克隆
NGFR5, monoclonal
表单
buffered aqueous solution
种属反应性
human, ( Non-human primates), ( Rabbit), ( Cat)
浓度
1 mg/ml
技术
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG1
UniProt登记号
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... NGFR(4804)
一般描述
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
特异性
The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.
免疫原
Purified CD271 protein isolated from human melanoma cell line A875
外形
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
制备说明
Purified by protein-A affinity chromatography.
储存及稳定性
Store at 2-8°C. Do not freeze.
其他说明
The antibody solution should be gently mixed before use.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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