Monoclonal Anti-CD82 purified low endotoxin produced in mouse

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.

The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

C91/PL (human HTLV-1+ T cell line)

Phosphate buffered saline (PBS), pH 7.4

Purified by protein-A affinity chromatography.

Store at 2-8°C. Do not freeze.

The antibody solution should be gently mixed before use.