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生物来源
mouse
质量水平
抗体形式
purified from hybridoma cell culture
抗体产品类型
primary antibodies
克隆
MANDYS8, monoclonal
形式
buffered aqueous solution
分子量
~427 kDa
种属反应性
porcine, rabbit, mouse, rat, human
增强验证
independent
Learn more about Antibody Enhanced Validation
浓度
~1.0 mg/mL
技术
immunoblotting: suitable
immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections
同位素/亚型
IgG2b
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DMD(1756)
相关类别
一般描述
Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).
Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.
特异性
Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.
免疫原
recombinant human dystrophin
应用
Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.
生化/生理作用
Dystrophin is known to prevent muscle fibre injury due to contraction.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.
其他说明
This product is for R&D use only, not for drug, household, or other uses.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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