SAB4200703
Anti-Neurotensin/NTS antibody, Mouse monoclonal
clone NTS-11, purified from hybridoma cell culture
别名:
Anti- neurotensin, Anti-NMN125, Anti-NN, Anti-NT, Anti-NT/N
产品名称
Anti-Neurotensin/NTS antibody, Mouse monoclonal, clone NTS-11, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
NTS-11, monoclonal
form
buffered aqueous solution
species reactivity
rat, human
concentration
~1 mg/mL
technique(s)
immunoblotting: 5-10 μg/mL using whole extract of SK-N-SH cells
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded rat brain sections
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NTS(4922)
rat ... Nts(299757)
Application
Anti-Neurotensin/NTS antibody, Mouse monoclonal has been used in:
- immunoblotting
- immunohistochemistry
- immunofluorescence
Biochem/physiol Actions
Neurotensin (NTS) functions as a neurotransmitter/neuromodulator in the central nervous system (CNS) and as an endocrine agent in the gastrointestinal (GI) tract. Neurotensin is involved in a variety of physiological processes such as, stress and pain modulation, pathophysiology of drug addiction, schizophrenia, Parkinson disease, depression, locomotion and reward. In the brain, neurotensin modulates dopaminergic transmission in the nigrostriatal and mesocorticolimbic pathways as well as hormone secretion from the anterior pituitary.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Anti-Neurotensin/NTS antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the NTS-11 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with synthetic peptide. Neurotensin (also known as NTS or NT) is a 13 amino acid brain-gut peptide.
Immunogen
Synthetic peptide from C-terminal region of human Neurotensin, conjugated to KLH
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The role of neurotensin as a novel biomarker in the endoscopic screening of high-risk population for developing colorectal neoplasia
Kontovounisios C, et al.
Updates in Surgery, 69(3), 397-397 (2017)
The role of neurotensin in central nervous system pathophysiology: What is the evidence?
St-Gelais F, et al.
Journal of Psychiatry & Neuroscience, 31(4), 229-229 (2006)
Diverse Roles of Neurotensin Agonists in the Central Nervous System
Boules M, et al.
Frontiers in Endocrinology, 4 (2013)
Collateral projections innervate the mammillary bodies and retrosplenial cortex: A new category of hippocampal cells
Kinnavane L, et al,.
eNeuro, 5(1) (2018)
Lisa Kinnavane et al.
eNeuro, 5(1) (2018-03-13)
To understand the hippocampus, it is necessary to understand the subiculum. Unlike other hippocampal subfields, the subiculum projects to almost all distal hippocampal targets, highlighting its critical importance for external networks. The present studies, in male rats and mice, reveal
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