产品名称
抗生物素抗体,小鼠单克隆抗体, clone BN-34, purified from hybridoma cell culture
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BN-34, monoclonal
form
buffered aqueous solution
species reactivity
canine, human, bovine, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: 0.15-0.3 μg/mL
western blot: suitable
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Biochem/physiol Actions
生物素作为乙酰辅酶A、丙酮酸、丙酰辅酶A和3-甲基巴豆酰基-辅酶A羧化酶的辅酶可用于调节糖异生、脂质稳态、多效基因表达以及补充三羧循环的中间体。与组蛋白结合的生物素在染色质重塑、DNA修复和转座子抑制以维持基因组的稳定性中发挥重要作用。生物素水平不足可导致皮炎、结膜炎、脱发和中枢神经系统异常。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
General description
生物素是一种重要的双杂环水溶性维生素,是大多数植物和原核生物合成的辅助因子。蛋白质结合生物素通常存在于膳食来源中,如肉类、谷物、蛋黄、肝脏和一些蔬菜。
Immunogen
生物素化KLH
Physical form
溶于0.01 M磷酸盐缓冲液(pH 7.4)中,含有15 mM叠氮化钠。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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Molecular biology of biotin attachment to proteins
Chapman-Smith Anne and Cronan Jr JE
The Journal of Nutrition, 129(2), 477S-484S (1999)
Michael Reinartz et al.
The Journal of biological chemistry, 283(25), 17440-17449 (2008-04-23)
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