生物来源
mouse
质量水平
抗体形式
purified from hybridoma cell culture
抗体产品类型
primary antibodies
克隆
DI-22, monoclonal
种属反应性
human, mouse, rat
浓度
1.0 mg/mL
~1 mg/mL
技术
ELISA: 0.15-0.3 μg/mL
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
一般描述
Monoclonal Anti-Digoxin (mouse IgG1 isotype) is derived from the hybridoma DI-22 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with digoxin conjugated to keyhole limpet hemocyanin (KLH).
免疫原
immunized with Digoxin
应用
Monoclonal Anti-Digoxin antibody produced in mouse has been used in:
- enzyme linked immunosorbent assay (ELISA)
- dot blot
- flow cytometry
- immunofluorescence
- DNA hybridization
- in-situ hybridization (ISH)
生化/生理作用
Digoxin is an uncharged glycoside which is given to humans with congestive heart failure. It enhances the force of myocardial contraction. Anti-digoxin antibodies can be used to reverse the effects of digoxin.
Unlike other oral inotrope, digoxin does not promote mortality. It inhibits sodium potassium ATPase membrane pump.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Digoxin
Eichhorn EJ and Gheorghiade M
Progress in Cardiovascular Diseases, 44(4), 251-266 (2002)
High-affinity monoclonal antibodies to the cardiac glycoside, digoxin.
M M Hunter et al.
Journal of immunology (Baltimore, Md. : 1950), 129(3), 1165-1172 (1982-09-01)
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