推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
表单
buffered aqueous solution
种属反应性
human, mouse
浓度
~1.0 mg/mL
技术
immunoblotting: 2.5-5.0 μg/mL using whole extracts of mouse P19 cells.
immunofluorescence: 2.5-5.0 μg/mL using human HeLa cells.
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CHD1(1105)
mouse ... Chd1(12648)
一般描述
Chromodomain-helicase-DNA-binding protein 1 (CHD1) is an ATP-dependent chromatin-remodeling factor. The CHD family of proteins contains two domains : chromo (chromatin organization modifier) and SNF2-related helicase/adenosine triphosphatase (ATPase).
免疫原
synthetic peptide corresponding to the C-terminal region of human CHD1 , conjugated to KLH.
应用
Anti-CHD1 (C-terminal) antibody from rabbit has been used in immunoblotting and immunofluorescence.
生化/生理作用
Chromodomain-helicase-DNA-binding protein 1 (CHD1) modifies chromatin structure affecting the interaction of transcriptional apparatus to its chromosomal DNA template. CHD1 is required for maintaining open chromatin and pluripotency in embryonic stem cells (ESCs).
外形
a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Concetta G A Marfella et al.
Mutation research, 618(1-2), 30-40 (2007-03-14)
Chromatin remodeling enzymes contribute to the dynamic changes that occur in chromatin structure during cellular processes such as transcription, recombination, repair, and replication. Members of the chromodomain helicase DNA-binding (Chd) family of enzymes belong to the SNF2 superfamily of ATP-dependent
Lena Ho et al.
Nature, 463(7280), 474-484 (2010-01-30)
New methods for the genome-wide analysis of chromatin are providing insight into its roles in development and their underlying mechanisms. Current studies indicate that chromatin is dynamic, with its structure and its histone modifications undergoing global changes during transitions in
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门