产品名称
抗-巢蛋白（C端） 兔抗, ~1.5 mg/mL, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~300 kDa
species reactivity
mouse, rat
packaging
antibody small pack of 25 μL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
~1.5 mg/mL
technique(s)
indirect immunofluorescence: 1-2 μg/mL using mouse P19 cells
western blot: 2-4 μg/mL using lysates of HEK293T cells over-expressing rat nestin.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Nes(18008)
rat ... Nes(25491)
Application
抗-巢蛋白（C端）抗体可用于免疫染色分析。
Biochem/physiol Actions
巢蛋白/NES在调节中间丝的组装和拆卸中起主要作用，进而帮助细胞与其他结构蛋白一起重塑。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
巢蛋白/NES属于中间丝（IF）蛋白家族的成员。在未成熟的神经上皮和祖细胞类型中发现其表达。这个240 kDa的蛋白质包含最短的头部结构域（N末端）和一个长的尾部结构域（C末端）。巢蛋白位于人染色体1q23.1。
Immunogen
该合成肽与KLH偶联，其对应于小鼠巢蛋白的C端序列。该序列在大鼠巢蛋白中是相同的。
Physical form
0.01M磷酸盐缓冲盐水溶液，pH 7.4，含有15 mM叠氮化钠。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Nestin-expressing cell types in the temporal lobe and hippocampus: Morphology, differentiation, and proliferative capacity.
Liu J, et al.
Glia, 66(1), 62-77 (2018)
Nestin structure and predicted function in cellular cytoskeletal organisation.
Michalczyk K and Ziman M
Histology and Histopathology, 20(2), 665-671 (2005)
Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells.
Tohyama T, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 66(3), 303-313 (1992)
YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation.
Huang Z, et al.
Development, 143(13), 2398-2409 (2016)
Intermediate filaments in peripheral nervous system: Their expression, dysfunction and diseases
Parlakian A, et al.
Revista de Neurologia, 172(10), 607-613 (2016)
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