SAB4200376
Anti-Atg13 antibody, Mouse monoclonal
clone ATG13-8, purified from hybridoma cell culture
别名:
Monoclonal Anti-Atg13 antibody produced in mouse, Monoclonal Anti-Autophagy related 13 homolog (S. cerevisiae), Monoclonal Anti-KIAA0652
登录查看公司和协议定价
所有图片(2)
About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
推荐产品
生物来源
mouse
偶联物
unconjugated
抗体形式
purified from hybridoma cell culture
抗体产品类型
primary antibodies
克隆
ATG13-8, monoclonal
表单
buffered aqueous solution
分子量
antigen ~65 kDa
种属反应性
human, mouse, rat
浓度
~1.0 mg/mL
技术
immunoprecipitation (IP): 5-10 μg using lysates of mouse LA-4 cells.
western blot: 1-2 μg/mL using whole extracts of HEK-293T cells over expressing human Atg13.
同位素/亚型
IgG2a
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ATG13(9776)
mouse ... Atg13(51897)
rat ... Atg13(362164)
一般描述
Monoclonal Anti-ATG13 (mouse IgG2a isotype) is derived from the hybridoma ATG13-8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice.
免疫原
synthetic peptide corresponding to the C-terminal region of human ATG13, conjugated to KLH. The corresponding sequence is identical in mouse and rat Atg13.
应用
Monoclonal Anti-Atg13 antibody produced in mouse has been used in immunoblotting and immunoprecipitation.
生化/生理作用
Atg13 is essential for autophagosome formation in mammalian cells. Atg13 forms a stable complex with UNC-51-like kinase 1 (ULK1) and family-interacting protein of 200 kDa (FIP200).
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
Hosokawa N, et al.
Molecular Biology of the Cell, 20(7), 1981-1991 (2009)
Tomokazu Murakawa et al.
Cell reports, 26(2), 338-345 (2019-01-10)
Degradation of mitochondria by selective autophagy, termed mitophagy, contributes to the control of mitochondrial quality. Bcl2-L-13 is a mammalian homolog of Atg32, which is an essential mitophagy receptor in yeast. However, the molecular machinery involved in Bcl2-L-13-mediated mitophagy remains to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门