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Merck
CN

SAB4200216

单克隆抗-β-小窝蛋白-1 小鼠抗

clone CAV1, tissue culture supernatant

别名:

抗-BSCL3, 抗-CAV1, 抗-CGL3, 抗-MSTP085, 抗-VIP21, 抗-小窝蛋白,22kDa

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
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产品名称

单克隆抗-β-小窝蛋白-1 小鼠抗, clone CAV1, tissue culture supernatant

biological source

mouse

conjugate

unconjugated

antibody form

tissue culture supernatant

antibody product type

primary antibodies

clone

CAV1, monoclonal

form

buffered aqueous solution

mol wt

antigen 22 kDa

species reactivity

rat, human, mouse

enhanced validation

independent
Learn more about Antibody Enhanced Validation

technique(s)

immunohistochemistry: suitable
indirect immunofluorescence: 1:1000-1:2000 using human HUVEC or mouse 3T3 cells.
western blot: suitable

isotype

IgM

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAV1(857)
mouse ... Cav1(12389)
rat ... Cav1(25404)

Application

单克隆抗小窝蛋白-1 抗体可用于蛋白质印迹分析。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
蛋白质免疫印迹分析(1篇论文)

Biochem/physiol Actions

小窝蛋白-1可能在癌症的生长和演化中发挥重要作用。它参与葡萄糖代谢。它也可能参与血管生成。Cav-1有助于控制葡萄糖转运蛋白的表达。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

小窝蛋白-1(CAV1)是一种多功能支架蛋白,具有三个外显子。它定位于人类染色体7q31。

Immunogen

合成肽,对应于人小窝蛋白-1 N 末端的序列,与 KLH 偶联。

Physical form

含有 15 mM 叠氮化钠的培养上清液。

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存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Ye Xiong et al.
Oncotarget, 8(15), 24902-24914 (2017-02-18)
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Wu Y, et al.
PLoS ONE, 10(8), e0136671-e0136671 (2015)
Joshua Chuck Harrell et al.
Cancer research, 67(21), 10582-10591 (2007-11-03)
The lymphatic system is a common avenue for the spread of breast cancer cells and dissemination through it occurs at least as frequently as hematogenous metastasis. Approximately 75% of primary breast cancers are estrogen receptor (ER) positive and the majority
Margaret E Tome et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 38(12), 2209-2222 (2018-10-23)
P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously
Claudia Matthaeus et al.
PloS one, 14(10), e0223620-e0223620 (2019-10-11)
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Quantitative and qualitative western blotting to validate knockdown by esiRNA.

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