SAB4200197
Anti-Periostin antibody,Mouse monoclonal
clone 47, purified from hybridoma cell culture
别名:
Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN
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所有图片(1)
About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
推荐产品
生物来源
mouse
偶联物
unconjugated
抗体形式
purified from hybridoma cell culture
抗体产品类型
primary antibodies
克隆
47, monoclonal
表单
buffered aqueous solution
分子量
antigen ~88 kDa
种属反应性
human
浓度
~1.0 mg/mL
技术
western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
同位素/亚型
IgG1
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... POSTN(10631)
一般描述
Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.
免疫原
human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.
应用
Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.
生化/生理作用
Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Bone marrow mesenchymal stem cells promote head and neck cancer progression through Periostin?mediated phosphoinositide 3?kinase/Akt/mammalian target of rapamycin.
Liu C, et al.
Cancer Science, 109(3), 688-698 (2018)
Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Makita K, et al.
International Archives of Allergy and Immunology, 175(1-2), 26-35 (2018)
Epithelial periostin expression is correlated with poor survival in patients with invasive breast carcinoma.
Kim G E, et al.
PLoS ONE, 12(11), e0187635-e0187635 (2017)
Imaging of secreted extracellular periostin, an important marker of invasion in the tumor microenvironment in esophageal cancer.
Heidari P, et al.
Journal of Nuclear Medicine, 56(8), 1246-1246 (2015)
Functional role of periostin in development and wound repair: implications for connective tissue disease.
Hamilton D W.
Journal of Cell Communication and Signaling, 2(1-2), 9-9 (2008)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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