Anti-Grem1 (C-terminal) antibody produced in rabbit biotin conjugated

Grem1 is a cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. It down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.

Synthetic peptide directed towards the C-terminal region of Mouse Grem1

Synthetic peptide located within the following region: EEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDL

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

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