产品名称
抗-ATP6V0D2 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
40 kDa
species reactivity
mouse, human, guinea pig, dog, rabbit, rat
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ATP6V0D2(245972)
Biochem/physiol Actions
腺苷三磷酸酶V0（ATP6V0D2）有助于破骨细胞成熟和骨形成。胰岛素通过细胞外信号调节激酶(ERK)1/2途径激活ATP6V0D2。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
腺苷三磷酸酶V0（ATP6V0D2）位于人类染色体8q21上。Atp6v0d2是液泡（H+）ATPase（v-ATPase）质子泵的同工型。ATP6V0D2在成熟的破骨细胞中大量表达。
Immunogen
合成肽靶向人ATP6V0D2的中间区域
Other Notes
合成肽位于以下区域内： MNVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPI
Physical form
本品为溶于1x PBS缓冲液的纯化抗体，含0.09% (w/v) 叠氮化钠和2%蔗糖。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
v-ATPase V 0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation
Lee, Seou, et al.
Nature Medicine, 12(12), 1403-1403 (2006)
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Oh, Ju He, et al.
Cellular Signalling, 27(12), 2325-2331 (2015)
Na Liu et al.
The Journal of clinical investigation, 129(2), 631-646 (2018-11-16)
Macrophages perform key functions in tissue homeostasis that are influenced by the local tissue environment. Within the tumor microenvironment, tumor-associated macrophages can be altered to acquire properties that enhance tumor growth. Here, we found that lactate, a metabolite found in
Weihao Zheng et al.
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Mycobacterium tuberculosis (Mtb) infects lung myeloid cells, but the specific Mtb-permissive cells and host mechanisms supporting Mtb persistence during chronic infection are incompletely characterized. We report that after the development of T cell responses, CD11clo monocyte-derived cells harbor more live
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