推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 54.1 kDa
种属反应性
human
技术
western blot: 1 μg/mL
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CEP55(55165)
一般描述
The gene CEP55 (Centrosomal protein of 55kDa), also referred to as C10orf3, encodes a 464 amino acid containing protein with highest expression in testis and thymus. This coiled-coil protein has a molar mass of 55kDa. The gene is mapped to human chromosome 10q23.33.
免疫原
CEP55 (NP_060601.2, 1 a.a. ~ 464 a.a) full-length human protein.
Sequence
MSSRSTKDLIKSKWGSKPSNSKSETTLEKLKGEIAHLKTSVDEITSGKGKLTDKERHRLLEKIRVLEAEKEKNAYQLTEKDKEIQRLRDQLKARYSTTALLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLLVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK
Sequence
MSSRSTKDLIKSKWGSKPSNSKSETTLEKLKGEIAHLKTSVDEITSGKGKLTDKERHRLLEKIRVLEAEKEKNAYQLTEKDKEIQRLRDQLKARYSTTALLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLLVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK
生化/生理作用
The gene CEP55 (Centrosomal protein of 55kDa) encodes a protein that is found to be localized to the mother centriole during interphase. It plays a crucial role in microtubule nucleation, mitotic exit and cytokinesis. The protein CEP55 also elicits the cell transformation by stimulating the phosphatidylinositol 3′-kinase (PI3K)/AKT pathway. It participates in the regulation of cell-cycle and is found in certain tumor tissues, such as hepatocellular carcinoma and gastric cancer. Additionally, it is also involved in midbody structure during cytokinesis.
外形
Solution in phosphate buffered saline, pH 7.4
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
CEP55 contributes to human gastric carcinoma by regulating cell proliferation.
Tao J
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 35, 4389-4399 (2014)
C-H Chen et al.
Oncogene, 26(29), 4272-4283 (2007-01-24)
A significant challenge in the post-genomic era is how to prioritize differentially expressed and uncharacterized novel genes found in hepatocellular carcinoma (HCC) microarray profiling. One such category is cell cycle regulated genes that have only evolved in higher organisms but
Megan Fabbro et al.
Developmental cell, 9(4), 477-488 (2005-10-04)
Centrosomes in mammalian cells have recently been implicated in cytokinesis; however, their role in this process is poorly defined. Here, we describe a human coiled-coil protein, Cep55 (centrosome protein 55 kDa), that localizes to the mother centriole during interphase. Despite
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