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安全信息

SAB1408102

Sigma-Aldrich

Anti-ZNF397 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

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别名:
MGC13250, ZNF47, ZSCAN15
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

100

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen ~31.1 kDa

种属反应性

human

技术

indirect immunofluorescence: suitable
western blot: 1 μg/mL

NCBI登记号

NM_032347.1

UniProt登记号

Q8NF99

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ZNF397(84307)

一般描述

Zinc finger protein 397 (ZNF397) belongs to the Cys2His2 group of the zinc-finger superfamily. It possesses a leucine-rich SCAN domain and nine Cys2His2 zinc fingers. The gene encoding this protein is localized on human chromosome 18q12.

免疫原

ZNF397 (NP_115723.1, 1 a.a. ~ 275 a.a) full-length human protein.

Sequence
MAVESGVISTLIPQDPPEQELILVKVEDNFSWDEKFKQNGSTQSCQELFRQQFRKFCYQETPGPREALSRLQELCYQWLMPELHTKEQILELLVLEQFLSILPEELQIWVQQHNPESGEEAVTLLEDLEREFDDPGQQVPASPQGPAVPWKDLTCLRASQESTDIHLQPLKTQLKSWKPCLSPKSDCENSETATKEGISEEKSQGLPQEPSFRGIKLSRPPKASSAIRWECVSPGSFPGDIIAAEATHSTISCFAINTLPATILPSKNVNRKYFS

生化/生理作用

Zinc finger protein 397 (ZNF397) has been shown to co-localize with centromere protein-A (CENP-A) during early prophase and interphase. It might be involved in transcriptional regulation.

外形

Solution in phosphate buffered saline, pH 7.4

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Yimin Wu et al.
Gene, 310, 193-201 (2003-06-13)
We have identified two novel human SCAN domain genes ZNF396 and ZNF397, which are clustered within the region of chromosome 18q12. Three isoforms of ZNF396 transcript, 1.5, 2.5 and 3.9-kb, are expressed highly in liver. Four isoforms of ZNF397 transcript
S L Bailey et al.
Chromosoma, 117(4), 367-380 (2008-03-29)
The centromere is a complex structure required for equal segregation of newly synthesised sister chromatids at mitosis. One of the significant objectives in centromere research is to determine the complete repertoire of protein components that constitute the kinetochore. Here, we

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