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Merck
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安全信息

SAB1403982

Sigma-Aldrich

Monoclonal Anti-INS antibody produced in mouse

clone 7C8, purified immunoglobulin, buffered aqueous solution

别名:

ILPR, IRDN

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

7C8, monoclonal

形式

buffered aqueous solution

分子量

antigen ~1.65 kDa

种属反应性

human

技术

indirect ELISA: suitable

同位素/亚型

IgG3κ

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... INS(3630)

一般描述

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. (provided by RefSeq)

免疫原

KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)

Sequence
CFFYTPKTRREAEDLQ

外形

Solution in phosphate buffered saline, pH 7.4

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WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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