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安全信息

SAB1403666

Sigma-Aldrich

Monoclonal Anti-RCC1, (C-terminal) antibody produced in mouse

clone 1C1, purified immunoglobulin, buffered aqueous solution

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UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

1C1, monoclonal

形式

buffered aqueous solution

分子量

antigen ~38.1 kDa

种属反应性

human

技术

capture ELISA: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... RCC1(1104)

免疫原

RCC1 (AAH07300, 312 a.a. ~ 421 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
EGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS

外形

Solution in phosphate buffered saline, pH 7.4

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Cathy J Spangler et al.
Nature chemical biology, 19(5), 624-632 (2023-02-17)
The nucleosome acidic patch is a major interaction hub for chromatin, providing a platform for enzymes to dock and orient for nucleosome-targeted activities. To define the molecular basis of acidic patch recognition proteome wide, we performed an amino acid resolution
Aleksandra Skrajna et al.
Nucleic acids research, 48(17), 9415-9432 (2020-07-14)
Nuclear proteins bind chromatin to execute and regulate genome-templated processes. While studies of individual nucleosome interactions have suggested that an acidic patch on the nucleosome disk may be a common site for recruitment to chromatin, the pervasiveness of acidic patch

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