产品名称
ANTI-RBM23 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
48731 Da
species reactivity
human
technique(s)
western blot: 1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RBM23(55147)
Application
ANTI-RBM23 (CENTER) antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:1000.
Biochem/physiol Actions
RBM23 (RNA binding motif protein 23) is involved in the steroid hormone receptor-mediated transcription. It interacts with the steroid nuclear receptors to increase transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It also acts as splicing cofactor for steroid receptors.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
RBM23 (RNA binding motif protein 23) is a member of U2AF65 family of proteins consisting of a serine-arginine-rich domain (RS domain) at the amino-terminal end, several RRM-RNA binding motifs at the central region of the protein and RRM/PUMP domain at the carboxyl-terminal end.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts.
Didier Auboeuf et al.
Molecular and cellular biology, 25(13), 5307-5316 (2005-06-21)
Dennis H Dowhan et al.
Molecular cell, 17(3), 429-439 (2005-02-08)
Increasing evidence indicates that transcription and pre-mRNA processing are functionally coupled to modulate gene expression. Here, we report that two members of the U2AF65 family of proteins, hCC1.3, which we call CAPERalpha, and a related protein, CAPERbeta, regulate both steroid
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