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Merck
CN
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主要文件

安全信息

SAB1305554

Sigma-Aldrich

Anti-β-Actin (ACTB) Antibody

mouse monoclonal, 137CT26.1.1

别名:

ACTB

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选择尺寸

54 EA
¥1,713.42

¥1,713.42

国内现货，预计发货时间2025年4月27日详情

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选择尺寸

变更视图
54 EA
¥1,713.42

About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

¥1,713.42

国内现货，预计发货时间2025年4月27日详情

产品名称

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse, clone 137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution

生物来源

mouse

质量水平

100

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

137CT26.1.1, monoclonal

表单

buffered aqueous solution

分子量

41737 Da

种属反应性

mouse, human

技术

immunofluorescence: 1:10-1:50
immunohistochemistry: 1:25
western blot: 1:1000

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Supelclean™ ENVI-Carb™ SPE 管

Supelclean™ ENVI-Carb™ SPE 管 bed wt. 250 mg, volume 6 mL, pk of 30

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Supelclean™ ENVI-Carb™ SPE 管

Supelclean™ ENVI-Carb™ SPE 管 bed wt. 2 g, volume 12 mL, pk of 20

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Supelclean™ ENVI-Carb™ SPE 管

Supelclean™ ENVI-Carb™ SPE 管 bed wt. 500 mg, volume 6 mL, pk of 30

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matrix active group

carbon phase

matrix active group

carbon phase

matrix active group

carbon phase

matrix active group

carbon phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

particle size

120-400 mesh

particle size

120-400 mesh

particle size

120-400 mesh

particle size

120-400 mesh

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

material

polypropylene tube

material

polypropylene tube

material

polypropylene tube

material

polypropylene tube

volume

3 mL

volume

6 mL

volume

12 mL

volume

6 mL

一般描述

β-actin (ACTB), a member of the actin multigene family, is an isoform of actin-associated with non-muscle cells. ACTB is a housekeeping gene mapped to human chromosome 7p22.1.

应用

Monoclonal Anti-Beta-Actin antibody produced in mouse has been used in western blotting at a dilution of 1:1000.

生化/生理作用

β-actin (ACTB) forms the core of the cell cytoskeleton. The polymerization of β-actin is essential for cell physiology. It may serve as a potential chemotherapeutic agent. Mutation in the ACTB gene is implicated in sensory hearing loss, delayed-onset generalized dystonia and a combination of ventral midline malformations. A loss-of-function mutation in the ACTB gene may cause intellectual disability.

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    SG100806AD

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    Sequence and structural analysis of beta-actin protein of fishes, using bioinformatics tools and techniques
    Acharya UR, et al.
    International journal of biosciences, 4(11) (2014)
    Vincent Procaccio et al.
    American journal of human genetics, 78(6), 947-960 (2006-05-11)
    Actin, one of the major filamentous cytoskeletal molecules, is involved in a variety of cellular functions. Whereas an association between muscle actin mutations and skeletal and cardiac myopathies has been well documented, reports of human disease arising from mutations of
    Sara Cuvertino et al.
    American journal of human genetics, 101(6), 1021-1033 (2017-12-09)
    ACTB encodes β-actin, an abundant cytoskeletal housekeeping protein. In humans, postulated gain-of-function missense mutations cause Baraitser-Winter syndrome (BRWS), characterized by intellectual disability, cortical malformations, coloboma, sensorineural deafness, and typical facial features. To date, the consequences of loss-of-function ACTB mutations have
    Induction of drug resistance in human hepatoma cells cultured on a silicate fiber based 3d scaffold
    Mizutami T, et al.
    Advances in Biochemical Engineering null
    Ioannis Panagopoulos et al.
    Anticancer research, 40(3), 1239-1245 (2020-03-07)
    Since the first description of five pericytomas with the t(7;12)/ACTB-GLI1 fusion gene, only three new tumors were studied by both cytogenetics and molecular techniques. We report here genetic data on another case of this rare tumor. Cytogenetic, fluorescence in situ
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