SAB1303013
ANTI-IL17RB (CENTER) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
别名:
Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, IL17BR, IL17RB, IL17Rh1, Interleukin-17 receptor B, Interleukin-17B receptor, UNQ2501/PRO19612
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所有图片(1)
About This Item
UNSPSC代码:
12352203
NACRES:
NA.43
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
55885 Da
种属反应性
human
技术
flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... IL17RB(55540)
相关类别
一般描述
Interleukin 17 receptor B (IL-17RB) belongs to the IL-17 receptor family. IL17RB, the receptor for interleukin 17 B (IL17B) is expressed at a high level in the liver, kidney, and other peripheral organs. It is also expressed in memory and effector T lymphocytes. IL17RB gene is located on human chromosome 3p21.1.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
Interleukin 17 receptor B (IL-17RB) might be considered in thyroid cancer therapy as a potential therapeutic target. IL17RB exhibits much efficient binding avidity to interleukin 17 E (IL17E). IL-17RB is overexpressed in pancreatic, gastric, and prostate cancers.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
从最新的版本中选择一种：
Alfonso Lavorgna et al.
PLoS pathogens, 10(10), e1004418-e1004418 (2014-10-24)
Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Tax protein functions as a potent viral oncogene that constitutively
Qingli Bie et al.
Scientific reports, 6, 25447-25447 (2016-05-06)
Inflammation is a critical component involved in tumor progression. Interleukin-17 (IL-17) belongs to a relatively new family of cytokines that has been associated with the progression of cancers. However, the role of IL-17B/IL-17RB (IL-17 receptor B) signaling to stemness of
Lei Ren et al.
Molecular immunology, 90, 126-135 (2017-07-18)
IL-17RB, a member of the IL-17 receptor family that can be activated by IL-17B, has been proved to be involved in inflammatory diseases and cancers. However, the function of IL-17RB in thyroid cancer is still unknown. In this study, IL-17RB
Gary M Hunninghake et al.
BMC pulmonary medicine, 11, 17-17 (2011-04-09)
The relationships between total serum IgE levels and gene expression patterns in peripheral blood CD4+ T cells (in all subjects and within each sex specifically) are not known. Peripheral blood CD4+ T cells from 223 participants from the Childhood Asthma
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