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Merck
CN
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主要文件

安全信息

SAB1300971

Sigma-Aldrich

Anti-PIK3R2 (Y467) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-PI3-kinase p85 subunit β, Anti-PIK3R2, Anti-Phosphatidylinositol 3-kinase regulatory subunit β, Anti-PtdIns-3-kinase p85-β

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

技术

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pTyr467)

基因信息

human ... PIK3R2(5296)

一般描述

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.

免疫原

PIK3R2 (NP_005018, )
This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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