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Merck
CN
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安全信息

SAB1300839

Sigma-Aldrich

Anti-EIF4A1 (N-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

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别名:
Anti-EIF-4A-I, Anti-EIF4A-I, Anti-EIF4A1, Anti-Eukaryotic initiation factor 4A-I, ATP-dependent RNA helicase eIF4A-1
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

saturated ammonium sulfate (SAS) precipitated

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

human

技术

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... EIF4A1(1973)

一般描述

EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5′-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

免疫原

EIF4A1 (NP_001407, 5-35)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EIF4A1.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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L Y Liu et al.
Journal of animal physiology and animal nutrition, 98(2), 310-317 (2013-05-31)
The objective of this study was to investigate the regulatory mechanism underlying the increased muscle protein accumulation in pigs while were fed a high protein diet. The eukaryotic initiation factors (eIFs) have been reported to involve in muscle protein synthesis.
Jasmine George et al.
Cell reports, 37(5), 109934-109934 (2021-11-04)
Fragile X-related protein-1 (FXR1) gene is highly amplified in patients with ovarian cancer, and this amplification is associated with increased expression of both FXR1 mRNA and protein. FXR1 expression directly associates with the survival and proliferation of cancer cells. Surface

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