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Merck
CN
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安全信息

SAB1300740

Sigma-Aldrich

Anti-BIRC7 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-Baculoviral IAP repeat-containing protein 7, Anti-KIAP, Anti-Kidney inhibitor of apoptosis protein, Anti-ML-IAP, Melanoma inhibitor of apoptosis protein

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

human

技术

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... BIRC7(79444)

一般描述

BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

免疫原

BIRC7 (Q96CA5-2, 257-290)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC7.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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