SAB1300711
Anti-MSH3 (center) antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-DNA mismatch repair protein Msh3, Anti-DUP, Anti-Divergent upstream protein, Anti-MRP1, Mismatch repair protein 1
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About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
saturated ammonium sulfate (SAS) precipitated
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
技术
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MSH3(4437)
一般描述
MSH3 is a component of the post-replicative DNA mismatch repair system (MMR). THis protein heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, it forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
免疫原
MSH3 (NP_002430, 464-497)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human MSH3.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human MSH3.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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