SAB1300678
Anti-KLF4 antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-EZF, Anti-GKLF, Anti-Kruppel-like factor 4
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
indirect ELISA
western blot
western blot
Species reactivity:
human
Citations:
7
Technique(s):
indirect ELISA: 1:1000
western blot: 1:100-1:500
western blot: 1:100-1:500
Uniprot accession no.:
产品名称
Anti-KLF4 antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KLF4(9314)
Biochem/physiol Actions
Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.
Immunogen
KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells
Minal Patel
Stem Cell Reviews (2010)
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
Francesca Zammarchi
The American Journal of Pathology (2011)
Kruppel-like factor 4 (KLF4): What we currently know.
Ghaleb AM and Yang VW
Gene (2017)
Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Xu J
Journal of Cancer Research and Clinical Oncology (2008)
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Evans PM
The Journal of Biological Chemistry (2007)
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