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Merck
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安全信息

SAB1300588

Sigma-Aldrich

Anti-NUP54 (center A315) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

别名:

Anti-54 kDa nucleoporin, Anti-NUP54, Anti-Nucleoporin p54

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

saturated ammonium sulfate (SAS) precipitated

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

human

技术

indirect ELISA: 1:1000

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... NUP54(53371)

一般描述

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.

免疫原

NUP54 (NP_059122, 302-336)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NUP54.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Masaharu Hazawa et al.
EMBO reports, 19(1), 73-88 (2017-12-09)
p63, more specifically its ΔNp63α isoform, plays essential roles in squamous cell carcinomas (SCCs), yet the mechanisms controlling its nuclear transport remain unknown. Nucleoporins (NUPs) are a family of proteins building nuclear pore complexes (NPC) and mediating nuclear transport across

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