biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse
technique(s)
immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000, western blot: 1:100-1:500
NCBI accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... GPR81(243270), Hcar1(243270)
General description
G蛋白偶联受体（GPCR或GPR）包含7个跨膜结构域，通过异三聚体G蛋白转导细胞外信号。RNA印迹分析揭示了垂体中GPR81的表达情况。
Immunogen
GPR81 (NP_780729, 276-329)
该抗体是由KLH标记的小鼠GPR81-S296区域对应合成肽免疫的兔产生的。
该抗体是由KLH标记的小鼠GPR81-S296区域对应合成肽免疫的兔产生的。
Physical form
纯化的单克隆抗体是含有0.09％（W/V）叠氮化钠的PBS溶液
Disclaimer
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Rochelle A Peterson et al.
Frontiers in cellular neuroscience, 14, 215-215 (2020-08-28)
A class of Group III muscle afferent neurons has branching sensory terminals in the connective tissue between layers of mouse abdominal muscles ("CT3 muscle afferents"). These sensory endings are both mechanosensitive and metabosensitive. In the present study, responses of CT3
Cecilie Morland et al.
Nature communications, 8, 15557-15557 (2017-05-24)
Physical exercise can improve brain function and delay neurodegeneration; however, the initial signal from muscle to brain is unknown. Here we show that the lactate receptor (HCAR1) is highly enriched in pial fibroblast-like cells that line the vessels supplying blood
Lili Jin et al.
Molecular medicine reports, 26(2) (2022-07-02)
Under aerobic conditions, the preferential use of anaerobic glycolysis by tumour cells leads to a high level of lactate accumulation in tumour microenvironment. Lactate acts not only as a cellular energy source but also as a signalling molecule that regulates
Rupali Vohra et al.
Investigative ophthalmology & visual science, 60(4), 999-1008 (2019-03-19)
Besides being actively metabolized, lactate may also function as a signaling molecule by activation of the G-protein-coupled receptor 81 (GPR81). Thus, we aimed to characterize the metabolic effects of GPR81 activation in Müller cells. Primary Müller cells from mice were
Mohammad Harun-Or-Rashid et al.
Journal of neuroinflammation, 15(1), 313-313 (2018-11-15)
Glaucoma is a chronic degenerative disease for which inflammation is considered to play a pivotal role in the pathogenesis and progression. In this study, we examined the impact of a ketogenic diet on the inflammation evident in glaucoma as a
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