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Merck
CN
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安全信息

SAB1300037

Sigma-Aldrich

Anti-SENP2 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-Axam2, Anti-SMT3-specific isopeptidase 2, Anti-Sentrin-specific protease 2, Anti-Sentrin/SUMO-specific protease SENP2, Anti-Smt3ip2

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

mouse, human

技术

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... SENP2(59343)

一般描述

SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

免疫原

SENP2 (NP_067640, 508-544)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SENP2.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Jia-Wen Xiang et al.
Current molecular medicine, 18(8), 533-541 (2019-01-15)
Protein Sumoylation is one of the most important and prevalent posttranscriptional modification. Increasing evidence have shown that the SENPs (sentrin/SUMOspecific proteases) are critical for steady-state levels of SUMO modification of target proteins, and protein de-sumoylation modulates a great diversity of
Jia-Wen Xiang et al.
Current molecular medicine, 19(1), 48-53 (2019-03-12)
It has been well established that sumoylation acts as an important regulatory mechanism that controls many different cellular processes. We and others have shown that sumoylation plays an indispensable role during mouse eye development. Whether sumoylation is implicated in ocular
Fang-Yuan Liu et al.
Aging cell, 19(10), e13222-e13222 (2020-08-23)
Sumoylation is one of the key regulatory mechanisms in eukaryotes. Our previous studies reveal that sumoylation plays indispensable roles during lens differentiation (Yan et al. 2010. Proc Natl Acad Sci USA. 107:21034-21039; Gong et al. 2014. Proc Natl Acad Sci

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