生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
mouse, human
技术
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SENP2(59343)
一般描述
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
免疫原
SENP2 (NP_067640, 508-544)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SENP2.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SENP2.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Current molecular medicine, 18(8), 533-541 (2019-01-15)
Protein Sumoylation is one of the most important and prevalent posttranscriptional modification. Increasing evidence have shown that the SENPs (sentrin/SUMOspecific proteases) are critical for steady-state levels of SUMO modification of target proteins, and protein de-sumoylation modulates a great diversity of
Current molecular medicine, 19(1), 48-53 (2019-03-12)
It has been well established that sumoylation acts as an important regulatory mechanism that controls many different cellular processes. We and others have shown that sumoylation plays an indispensable role during mouse eye development. Whether sumoylation is implicated in ocular
Aging cell, 19(10), e13222-e13222 (2020-08-23)
Sumoylation is one of the key regulatory mechanisms in eukaryotes. Our previous studies reveal that sumoylation plays indispensable roles during lens differentiation (Yan et al. 2010. Proc Natl Acad Sci USA. 107:21034-21039; Gong et al. 2014. Proc Natl Acad Sci
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