Anti-NUPR1 (47-60) antibody produced in rabbit

The NUPR1 (nuclear protein 1, transcriptional regulator) gene is mapped to human chromosome 16p11.2 and encodes a chromatin remodeling protein of 8.8 KDa.

synthetic peptide corresponding to amino acids 47-60 of human NUPR1

Anti-NUPR1 (47-60) antibody produced in rabbit has been used in western blot analysis.

Nupr1 (nuclear protein 1, transcriptional regulator) is a stress response factor, induced by lipopolysaccharides, CCl₄, starvation, cell cycle arrest and other protein stimuli. NUPR1 is associated with tumor cell proliferation, metastasis and apoptosis, also regulates entosis, matrix remodeling and autophagy. It serves as a substrate for protein kinase A. Overexpression of this gene is observed in glioblastoma and hepatocellular carcinoma. The protein function is tissue specific and differs at molecular level. It can act as a tumor suppressor or inducer.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

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