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安全信息

SAB1100050

Sigma-Aldrich

Anti-LDHA (216-228) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-LDH-M, Anti-LDH1, Anti-Lactate dehydrogenase A, Anti-PIG19

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen ~37 kDa

种属反应性

human

技术

western blot: 1:500-1:2,000

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... LDHA(3939)

一般描述

Lactate dehydrogenase A (LDHA) or the M subunit is a cytosolic enzyme and is abundantly present in the skeletal muscle. Lactate dehydrogenase B (LDHB) or the H subunit is mainly seen in the heart. Both genes are capable of forming homotetramers or heterotetramers. LDHA gene is located on human chromosome 11p15.4.

免疫原

synthetic peptide corresponding to amino acids 216-228 of human LDHA

应用

Anti-LDHA (216-228) antibody produced in rabbit has been used in:
  • in situ

  • proximity ligation assay (PLA)
  • immuno-staining
  • western blotting

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

生化/生理作用

Lactate dehydrogenase A (LDHA) participates in anaerobic and aerobic glycolysis. It can regenerate nicotinamide adenine dinucleotide (NAD+) from NADH to maintain the ATP synthesis in the absence of adequate oxygen. The N-terminus of LDHA is essential for the stability of the structure.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

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