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Merck
CN

S9637

Sigma-Aldrich

琥珀酸钠 二元 六水合物

BioReagent, suitable for cell culture, suitable for insect cell culture

别名:

丁二酸 二钠盐, 琥珀酸 二钠盐

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About This Item

线性分子式:
NaOOCCH2CH2COONa · 6H2O
CAS号:
分子量:
270.14
Beilstein:
3921044
EC 号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
NACRES:
NA.71

产品线

BioReagent

质量水平

技术

cell culture | insect: suitable
cell culture | mammalian: suitable

pH值(酸碱度)

8—9.5 (25 °C, 270 g/L)

溶解性

H2O: 100 mg/mL, clear, colorless

SMILES字符串

O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O

InChI

1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2

InChI key

ZBTUYCUNQBRXOR-UHFFFAOYSA-L

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一般描述

琥珀酸二钠六水合物是双羧酸琥珀酸的钠盐。广泛用于细胞生物学、细胞培养和生化研究。在细胞培养和细胞生物学研究中用作能源和缓冲液,尤其适合三羧酸循环(Krebs循环)研究。据推测,琥珀酸二钠六水合物可能作为离子载体促进离子跨膜运输,从而影响细胞代谢。又名琥珀酸二钠盐,在对于细胞功能至关重要的ATP(腺苷三磷酸)生产中,可作为关键底物。

应用

六水合丁二酸钠已用作:
  • 实验培养基中的补充剂,以培养线粒体并测定复合物-II的比活性
  • 植物诱导培养基/原生质体诱导培养(PIM)的组分,以用于植物再生
  • 新鲜培养基中的小分子添加剂,以研究其对中国仓鼠卵巢(CHO)细胞转基因表面的正向协同作用

特点和优势

  • 用途广泛,适用于多种实验室和研究应用
  • BioReagent级琥珀酸钠,适于细胞生物学和生物化学研究
  • 经检测可用于哺乳动物和昆虫细胞培养应用

其他说明

如需了解生化试剂系列的更多信息,请填写此表

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Wei-Feng Li et al.
New biotechnology, 69, 8-17 (2022-02-27)
Chinese hamster ovary (CHO) cells are currently the most widely used host cells for production of recombinant therapeutic proteins (RTPs). Small-molecule additives related to cell cycle apoptosis and autophagy regulation have been used to promote RTP production. By combining two
Huimin Mao et al.
Stem cells international, 2020, 2016809-2016809 (2020-03-28)
Most mesenchymal stem cells reside in a niche of low oxygen tension. Iron-chelating agents such as CoCl2 and deferoxamine have been utilized to mimic hypoxia and promote cell growth. The purpose of the present study was to explore whether a
Jongjin Park et al.
Methods in molecular biology (Clifton, N.J.), 1917, 337-354 (2019-01-06)
CRISPR/Cas9 nuclease system is getting popular in precise genome editing of both eukaryotic and prokaryotic systems due to its accuracy, programmability, and relative ease of use. CRISPR/Cas systems can be delivered into live cells via plasmid DNA, RNA, and ribonucleoprotein
Georgia L Isom et al.
Cell, 181(3), 653-664 (2020-05-04)
Gram-negative bacteria are surrounded by an outer membrane composed of phospholipids and lipopolysaccharide, which acts as a barrier and contributes to antibiotic resistance. The systems that mediate phospholipid trafficking across the periplasm, such as MCE (Mammalian Cell Entry) transporters, have
Adrián Povo-Retana et al.
Cancers, 12(10) (2020-10-24)
Tumor-associated macrophages (TAMs) play a crucial role in suppressing the immunosurveillance function of the immune system that prevents tumor growth. Indeed, macrophages can also be targeted by different chemotherapeutic agents improving the action over immune checkpoints to fight cancer. Here

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