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S9318

Sandoz 58-035

Name: Sandoz 58-035
Brand: SIGMA

>98% (HPLC), powder, acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor

别名:

3-[癸基二甲基甲硅烷基] -N- [2-（4-甲基苯基）-1-苯乙基]丙酰胺, SA 58-035

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关于此项目

经验公式（希尔记法）:

C₃₀H₄₇NOSi

化学文摘社编号:

78934-83-5

分子量:

465.79

UNSPSC Code:

41121801

PubChem Substance ID:

24278227

NACRES:

NA.77

MDL number:

MFCD00161339

Assay:

>98% (HPLC)

Form:

powder

Quality level:

100

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属性

产品名称

Sandoz 58-035, >98% (HPLC), powder

Quality Level

100

assay

>98% (HPLC)

form

powder

color

white

solubility

DMSO: 16 mg/mL, H₂O: insoluble

originator

Novartis

storage temp.

2-8°C

SMILES string

CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c2ccccc2

InChI

1S/C30H47NOSi/c1-5-6-7-8-9-10-11-15-23-33(3,4)24-22-30(32)31-29(28-16-13-12-14-17-28)25-27-20-18-26(2)19-21-27/h12-14,16-21,29H,5-11,15,22-25H2,1-4H3,(H,31,32)

InChI key

NBYATBIMYLFITE-UHFFFAOYSA-N

Gene Information

human ... SOAT1(6646)
rat ... Soat1(81782)

说明

Application

Sandoz 58-035 用于诱导小鼠腹腔巨噬细胞中未折叠蛋白反应（UPR）和模式识别受体（PRR）的同时激活。³

Biochem/physiol Actions

Sandoz 58-035 抑制胆固醇酯的积累，抑制培养物中动脉平滑肌细胞 95％的胆固醇酯化。¹它不影响肠道甘油三酯代谢。²

酰基辅酶 A：胆固醇酰基转移酶（ACAT）抑制剂。

Features and Benefits

该化合物由 Novartis 开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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