S9317
PAR-2 (1-6) 酰胺（小鼠、大鼠） 三氟乙酸盐
≥97% (HPLC), proteinase-activated receptor 2 peptide agonist, solid
别名:
PAR2-AP, SLIGRL−NH2, Ser-Leu-Ile-Gly-Arg-Leu-酰胺 三氟乙酸盐
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C29H56O7N10 · C2HF3O2
分子量:
770.84
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
PAR-2 (1-6) 酰胺（小鼠、大鼠） 三氟乙酸盐, ≥97% (HPLC)
Quality Level
assay
≥97% (HPLC)
form
solid
storage temp.
−20°C
SMILES string
CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O
InChI
1S/C29H56N10O7/c1-7-17(6)23(39-27(45)21(12-16(4)5)38-25(43)18(30)14-40)28(46)35-13-22(41)36-19(9-8-10-34-29(32)33)26(44)37-20(24(31)42)11-15(2)3/h15-21,23,40H,7-14,30H2,1-6H3,(H2,31,42)(H,35,46)(H,36,41)(H,37,44)(H,38,43)(H,39,45)(H4,32,33,34)/t17-,18-,19-,20-,21-,23-/m0/s1
InChI key
SGPMJRPYYIJZPC-JYAZKYGWSA-N
Application
PAR-2 (1-6) 酰胺（小鼠、大鼠）三氟乙酸盐已被用作蛋白酶激活受体 2（PAR-2） 激动剂，以诱导 Hek293A 细胞中 Hh 和 Hippo 基因的表达。
Biochem/physiol Actions
选择性蛋白酶激活受体 2（PAR2） 肽激动剂。
flash_point_c
Not applicable
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Hyun Su Ha et al.
Archives of pharmacal research, 40(12), 1443-1454 (2017-11-04)
Protease-activated receptors (PARs) are a family of G protein-coupled receptors with a unique activation mechanism involving proteolytic cleavage of the extracellular N-terminal domain of the receptor. PAR2 has a contractile effect on esophageal smooth muscle. We investigate the signaling pathways
The Yes-associated protein controls the cell density regulation of Hedgehog signaling
M. Tariki
Oncogenesis (2014)
Chihiro Hirai et al.
Reproductive sciences (Thousand Oaks, Calif.), 23(11), 1542-1550 (2016-05-04)
The production of soluble fms-like tyrosine kinase 1 (sFLT1) by exogenous chymotrypsin in trophoblast cells through protease-activated receptor (PAR) 2 was investigated to identify the role of a chymotrypsin-like serine protease in preeclampsia (PE) pathogenesis. We evaluated the expression of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S9317-1MG | 04061826677025 |