所有图片(1)
About This Item
经验公式（希尔记法）:
C20H18O6
CAS号:
分子量:
354.35
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
生物来源
Sesamum indicum (sesame)
方案
≥95%
表单
crystalline
运输
wet ice
储存温度
−20°C
SMILES字符串
C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5
InChI
1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
InChI key
PEYUIKBAABKQKQ-AFHBHXEDSA-N
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一般描述
芝麻素是存在于芝麻种子中的脂溶性呋喃木酚素。
应用
芝麻素已被用于：
- 作为木酚素用于研究其对大鼠骨髓基质细胞（BMSC）成骨细胞分化的影响
- 作为分离芝麻油中芝麻素的标准品
- 研究其作为内源性木酚素（enterolignan）对雌激素受体（ER）阳性人乳腺癌MCF-7细胞增殖的影响
生化/生理作用
芝麻素可以降低人体内胆固醇的作用。它参与预防高血压，并增加维生素E水平。芝麻素具有抗癌、抗增殖、抗转移和抗炎特性。它还具有促凋亡和促自噬特性。芝麻素对脂质和碳水化合物的代谢有影响。它还对高血压和自由基清除有影响。
非竞争性δ 5-去饱和酶抑制剂。
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
S Shimizu et al.
Lipids, 26(7), 512-516 (1991-07-01)
Incubation with sesame oil increases the mycelial dihomo-gamma-linolenic acid content of an arachidonic acid-producing fungus, Mortierella alpina, but decreases its arachidonic acid content [Shimizu, S., K. Akimoto, H. Kawashima, Y. Shinmen and H. Yamada (1989) J. Am. Oil Chem. Soc.
Sesamin promotes osteoblastic differentiation and protects rats from osteoporosis
Ma Z, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 25(16), 5312-5312 (2019)
Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors
Zhu Y, et al.
Testing, 12(2), e0171390-e0171390 (2017)
Zhong-Ping Ma et al.
Medical science monitor : international medical journal of experimental and clinical research, 25, 5312-5320 (2019-07-18)
BACKGROUND Osteoporosis is a common osteopathy, resulting in fractures, especially in elder people. Sesamin has many pharmacological effects, including supplying calcium. However, how sesamin might prevent osteoporosis is still under study. MATERIAL AND METHODS Bone marrow stromal cells (BMSCs) extracted
Amin F Majdalawieh et al.
European journal of pharmacology, 815, 512-521 (2017-10-17)
Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its anti-proliferative, pro-apoptotic, anti-inflammatory, anti-metastatic, anti- and pro-angiogenic, and pro-autophagocytic activities.
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