product name
磺酰罗丹明 B 钠盐, Technical grade
质量水平
形式
powder
组成
Dye content, ~75%
εmax
≥85000 at 554-560 nm
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1
InChI
1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
InChI key
SXQCTESRRZBPHJ-UHFFFAOYSA-M
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一般描述
磺酰罗丹明B（Sulforhodamine B，别名SRB、奇通罗丹明B、丽丝胺罗丹明B或磺基罗丹明B）是一种亮粉色阴离子氨基氧杂蒽类染料，含有两个磺酸酯取代基。
应用
磺酰罗丹明B(SRB)可用于SRB检测，通过染色进行体外细胞毒性检测，以及活细胞观察、增殖和药物筛选。
SRB检测可评估漱口水对人成纤维细胞原代培养物中蛋白含量的影响。
它也可作为显微示踪剂，通过冷冻切片尸检评估血脑屏障的完整性。磺酰罗丹明B可作为染料搭配后续的组织学材料检查进行龋齿检测。
SRB检测可评估漱口水对人成纤维细胞原代培养物中蛋白含量的影响。
它也可作为显微示踪剂，通过冷冻切片尸检评估血脑屏障的完整性。磺酰罗丹明B可作为染料搭配后续的组织学材料检查进行龋齿检测。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Xinyuan Chen et al.
Journal of controlled release : official journal of the Controlled Release Society, 159(1), 43-51 (2012-01-21)
Full-surface laser ablation has been shown to efficiently disrupt stratum corneum and facilitate transcutaneous drug delivery, but it is frequently associated with skin damage that hampers its clinic use. We show here that a safer ablative fractional laser (AFL) can
Samantha N Andrews et al.
Pharmaceutical research, 30(4), 1099-1109 (2012-12-01)
Most methods to increase transdermal drug delivery focus on increasing stratum corneum permeability, without addressing the need to increase permeability of viable epidermis. Here, we assess the hypothesis that viable epidermis offers a significant permeability barrier that becomes rate limiting
Gang Chen et al.
Cancer research, 74(16), 4536-4548 (2014-06-21)
Cancer stem cells, capable of self-renewal and multipotent differentiation, influence tumor behavior through a complex balance of symmetric and asymmetric cell divisions. Mechanisms regulating the dynamics of stem cells and their progeny in human cancer are poorly understood. In Drosophila
Jesús Villar et al.
Critical care (London, England), 18(5), 568-568 (2014-10-22)
The mechanisms of lung repair and fibrosis in the acute respiratory distress syndrome (ARDS) are poorly known. Since the role of WNT/β-catenin signaling appears to be central to lung healing and fibrosis, we hypothesized that this pathway is activated very
Evangelia Sereti et al.
Biomedicines, 9(1) (2021-01-21)
Sigma (σ) receptors have attracted great interest since they are implicated in various cellular functions and biological processes and diseases, including various types of cancer. The receptor family consists of two subtypes: sigma-1 (σ1) and sigma-2 (σ2). Both σ receptor
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