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Merck
CN

S9012

磺酰罗丹明 B 钠盐

Powder

别名:

酸性红52;酸性罗丹明 B

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关于此项目

经验公式(希尔记法):
C27H29N2NaO7S2
化学文摘社编号:
分子量:
580.65
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
222-529-8
MDL number:
Colour Index Number:
45100
Beilstein/REAXYS Number:
3886008
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产品名称

磺酰罗丹明 B 钠盐, Technical grade

Quality Level

form

powder

composition

Dye content, ~75%

εmax

≥85000 at 554-560 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1

InChI

1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1

InChI key

SXQCTESRRZBPHJ-UHFFFAOYSA-M

General description

磺酰罗丹明B(Sulforhodamine B,别名SRB、奇通罗丹明B、丽丝胺罗丹明B或磺基罗丹明B)是一种亮粉色阴离子氨基氧杂蒽类染料,含有两个磺酸酯取代基。

Application

磺酰罗丹明B(SRB)可用于SRB检测,通过染色进行体外细胞毒性检测,以及活细胞观察、增殖和药物筛选。

SRB检测可评估漱口水对人成纤维细胞原代培养物中蛋白含量的影响。

它也可作为显微示踪剂,通过冷冻切片尸检评估血脑屏障的完整性。磺酰罗丹明B可作为染料搭配后续的组织学材料检查进行龋齿检测。


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Most methods to increase transdermal drug delivery focus on increasing stratum corneum permeability, without addressing the need to increase permeability of viable epidermis. Here, we assess the hypothesis that viable epidermis offers a significant permeability barrier that becomes rate limiting
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Journal of controlled release : official journal of the Controlled Release Society, 159(1), 43-51 (2012-01-21)
Full-surface laser ablation has been shown to efficiently disrupt stratum corneum and facilitate transcutaneous drug delivery, but it is frequently associated with skin damage that hampers its clinic use. We show here that a safer ablative fractional laser (AFL) can
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Cancer stem cells, capable of self-renewal and multipotent differentiation, influence tumor behavior through a complex balance of symmetric and asymmetric cell divisions. Mechanisms regulating the dynamics of stem cells and their progeny in human cancer are poorly understood. In Drosophila



全球贸易项目编号

货号GTIN
S9012-25G04061836961183
S9012-1G04061824379457
S9012-5G04061836961190