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质量水平
检测方案
≥90% (HPLC)
形式
powder
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
SMILES字符串
C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO
InChI
1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+
InChI key
AFPLNGZPBSKHHQ-MEGGAXOGSA-N
一般描述
茄尼醇(Solanesol)主要从烟草(Nicotiana tabacum)中提取而来。它是一种脂肪萜类、聚异戊二烯醇。茄尼醇还分布于其他茄科植物中，如番茄 、土豆 、茄子、甜椒(bell pepper)。这种C45异戊二烯醇是烟叶中蕴含最丰富的脂质。
应用
烟草茄尼醇可作为参考标准品，通过反相高效液相色谱(RP-HPLC)定量分析不同烟叶样品中的茄尼醇。它可增强人造脂质体稳定性，用于检测渗透压应激下泛醌-8(Q8)介导的大肠杆菌膜的机械稳定性。
生化/生理作用
茄尼醇具有抗氧化、抗炎、神经保护和抗菌作用。还可结合硫代水杨酸(TS)和透明质酸(HA)作为药物载体，发挥抗癌作用。茄尼醇是烟气中的致瘤性多核芳香烃的重要前体。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Yao Xiong et al.
International journal of pharmaceutics, 572, 118823-118823 (2019-11-13)
Metabolites of a large number of inert drug carriers can cause long-term exogenous biological toxicity. Therefore, carriers with simultaneous therapeutic effects may be a good choice for drug delivery. Herein, a series of pharmacologically active solanesol derivatives were synthesized and
Daniel C Sévin et al.
Nature chemical biology, 10(4), 266-272 (2014-02-11)
Bacteria are thought to cope with fluctuating environmental solute concentrations primarily by adjusting the osmolality of their cytoplasm. To obtain insights into the underlying metabolic adaptations, we analyzed the global metabolic response of Escherichia coli to sustained hyperosmotic stress using
Weihong Zhong et al.
Applied microbiology and biotechnology, 89(2), 293-302 (2010-09-22)
In a water-organic solvent, two-phase conversion system, CoQ(10) could be produced directly from solanesol and para-hydroxybenzoic acid (PHB) by free cells of Sphingomonas sp. ZUTE03 and CoQ(10) concentration in the organic solvent phase was significantly higher than that in the
Mark A Taylor et al.
Phytochemistry, 72(11-12), 1323-1327 (2011-04-05)
Isoprenoids, also known as terpenoids, are the largest and oldest class of natural products known. They are comprised of more than 40,000 different molecules all biosynthetically related via a common five carbon building block (isopentenyl). Many isoprenoids are of commercial
Junhui Chen et al.
Journal of separation science, 31(1), 137-142 (2007-12-21)
HPLC coupled online with atmospheric pressure chemical ionization MS (APCI-MS) technique was evaluated for the qualitative and quantitative determination of solanesol in extracts of tobacco leaves. The solanesol and other compounds in the extract were separated on an Alltima C(8)
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