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Merck
CN

S8754

Sigma-Aldrich

茄尼醇 来源于烟草

≥90% (HPLC)

别名:

Betulanonaprenol, Nonaisoprenol

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About This Item

经验公式(希尔记法):
C45H74O
CAS号:
分子量:
631.07
MDL编号:
UNSPSC代码:
12352212
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

≥90% (HPLC)

表单

powder

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO

InChI

1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+

InChI key

AFPLNGZPBSKHHQ-MEGGAXOGSA-N

一般描述

茄尼醇(Solanesol)主要从烟草(Nicotiana tabacum)中提取而来。它是一种脂肪萜类、聚异戊二烯醇。茄尼醇还分布于其他茄科植物中,如番茄 、土豆 、茄子、甜椒(bell pepper)。这种C45异戊二烯醇是烟叶中蕴含最丰富的脂质。

应用

烟草茄尼醇可作为参考标准品,通过反相高效液相色谱(RP-HPLC)定量分析不同烟叶样品中的茄尼醇。它可增强人造脂质体稳定性,用于检测渗透压应激下泛醌-8(Q8)介导的大肠杆菌膜的机械稳定性。

生化/生理作用

茄尼醇具有抗氧化、抗炎、神经保护和抗菌作用。还可结合硫代水杨酸(TS)和透明质酸(HA)作为药物载体,发挥抗癌作用。茄尼醇是烟气中的致瘤性多核芳香烃的重要前体。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Mengying Zhang et al.
International journal of biological macromolecules, 201, 20-28 (2022-01-10)
The administration of nanodrugs can lead to metabolism related systemic toxicity due to the use of inert carriers in large quantities. Carrier materials that offer therapeutic effects are therefore a promising means of addressing this limitation. Herein, a hyaluronate-based nanocarrier
Gregory M Polzin et al.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 11(7), 868-874 (2009-06-23)
Standardized machine smoking measurements are poor predictors of exposure. We have refined a method using the solanesol deposited in discarded cigarette butts as a marker for estimating deliveries of mainstream smoke constituents. Developing a fast and accurate method for measuring
Study on supercritical fluid extraction of solanesol from industrial tobacco waste
Wang, Yu and Gu, Wenbo
Journal of Supercritical Fluids, 138, 228-237 (2018)
Jiangyong Hu et al.
Se pu = Chinese journal of chromatography, 25(4), 528-531 (2007-11-01)
Preparative high-speed counter-current chromatography (HSCCC) was used for the isolation and purification of solanesol from potato leaves. Experimental conditions of the extraction of solanesol from potato leaves have been optimized. An ultrafine extraction method was applied in this study. The
Naoyuki Ishida
Journal of chromatography. A, 1217(37), 5794-5801 (2010-08-10)
A direct and simple method for analyzing solanesyl esters found in tobacco leaves was developed. Sample preparation was performed by accelerated solvent extractor 200 (ASE200) using n-hexane followed by evaporating solution in vacuo and dissolving residue with acetone. The separation

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