S8647
Sulfacetamide sodium salt monohydrate
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C8H9N2NaO3S · H2O
化学文摘社编号:
分子量:
254.24
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
MDL number:
InChI
1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1
SMILES string
NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O
InChI key
IHCDKJZZFOUARO-UHFFFAOYSA-M
form
powder
color
white to off-white
solubility
H2O: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycoplasma
mode of action
DNA synthesis | interferes, enzyme | inhibits
General description
Chemical structure: sulfonamide
Biochem/physiol Actions
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Packaging
100G
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Margareta Ungureanu et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 110(2), 456-459 (2007-09-07)
In the present study we emphasized the antituberculosis action of new sulphacetamide derivatives. In order o extend the research for obtaining antituberculosis substances, we decided to study the influence of the introducing of the thiourea and sulphamide groups in the
M Gooderham
Skin therapy letter, 14(2), 1-3 (2009-03-31)
Many options exist for the treatment of rosacea, including topical and systemic therapies, laser and light-based therapies, and surgical procedures. A classification system for rosacea identifies 4 subtypes (i.e., erythematotelangiectatic, papulopustular, phymatous, and ocular), which may help guide therapeutic decision-making.
James Q Del Rosso
Cutis, 86(5 Suppl), 16-25 (2011-01-15)
Rosacea is a prevalent inflammatory skin disorder that affects approximately 16 million individuals in the United States. Although its exact etiology is unknown, basic science, histologic evidence, and clinical evidence suggest that it is inflammatory in nature. In this 12-week
Zoe Diana Draelos
Journal of drugs in dermatology : JDD, 9(3), 234-236 (2010-03-18)
Prior to 1962, some of the most versatile drugs in dermatology were approved by the U.S. Food and Drug Administration (FDA) solely on the basis of safety. One of these is the combination 10% sodium sulfacetamide and 5% sulfur. Sodium
Ilknur Akyol-Salman et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 28(1), 49-52 (2011-07-15)
This study aimed to compare the efficacy of topical N-acetyl-cysteine (NAC) with a topical steroid-antibiotic combination, betamethasone-sulfacetamide sodium therapy in patients with meibomian gland dysfunction (MGD). Twenty patients with MGD were prospectively randomized and assigned into 2 groups. The patients
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持