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Merck
CN
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文件

S7635

Sigma-Aldrich

磺酰罗丹明 101

Dye content ~95 %, Powder

别名:

SR101; 2-(3-氧杂-23-氮杂-9-氮阳离子庚环[17.7.1.15,9.02,17.04,15.023,27.013,28]二十八烷-1(27),2(17),4,9(28),13,15,18-庚烷-16-基)-5-磺基苯磺酸盐

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About This Item

经验公式（希尔记法）:
C31H30N2O7S2
CAS号:
60311-02-6
分子量:
606.71
Beilstein:
3582548
EC 号:
262-159-4
MDL编号:
MFCD00012407
UNSPSC代码:
12171500
PubChem化学物质编号:
24899749
NACRES:
NA.47

product name

磺酰罗丹明 101, Dye content ~95 %

形式

powder

质量水平

100

组成

Dye content, ~95%

颜色

black
dark green to brown

溶解性

methanol: 1 mg/mL

ε (消光系数)

≥105000 at 573-579 nm in ethanol

荧光

λex 586 nm; λem 605 nm in H2O

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI key

COIVODZMVVUETJ-UHFFFAOYSA-N

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相关类别

一般描述

磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。

应用

磺酰罗丹明101已用于：
  • 标记星形胶质细胞
  • 定量聚合酶链式反应(PCR)
  • 测定组织样品的损伤率

生化/生理作用

磺酰罗丹明101可特异性标记新皮质星形胶质细胞。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Florence Appaix et al.
PloS one, 7(4), e35169-e35169 (2012-04-18)
Fluorescent staining of astrocytes without damaging or interfering with normal brain functions is essential for intravital microscopy studies. Current methods involved either transgenic mice or local intracerebral injection of sulforhodamine 101. Transgenic rat models rarely exist, and in mice, a
Danielle Tokarz et al.
PloS one, 12(10), e0186846-e0186846 (2017-10-25)
Osteocytes are the most abundant cell in the bone, and have multiple functions including mechanosensing and regulation of bone remodeling activities. Since osteocytes are embedded in the bone matrix, their inaccessibility makes in vivo studies problematic. Therefore, a non-invasive technique
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn A, et al.
Nature Methods, 1(1), 31-31 (2004)
Jumpei Ukita et al.
Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
David S Greenberg et al.
Nature neuroscience, 11(7), 749-751 (2008-06-17)
It is unclear how the complex spatiotemporal organization of ongoing cortical neuronal activity recorded in anesthetized animals relates to the awake animal. We therefore used two-photon population calcium imaging in awake and subsequently anesthetized rats to follow action potential firing
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