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Merck
CN

S7531

Sigma-Aldrich

抗 葡萄球菌 α-毒素 兔抗

whole antiserum

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别名:
抗 α-溶血素
MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

whole antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

分子量

antigen 33 kDa

包含

15 mM sodium azide

种属反应性

Staphylococcus aureus

包装

antibody small pack of 25 μL

技术

dot blot: 1:20,000
indirect ELISA: 1:50,000

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

相关类别

一般描述

葡萄球菌α-毒素是一种33kD的水溶性单一多肽,是金黄色葡萄菌分泌的细胞毒性物质。这种蛋白具有膜损伤属性,可导致红细胞溶解。因此,它也被称为致死性溶血毒素或α-溶血素。葡萄球菌α-毒素抗体可用于毒素-膜相互作用的研究。兔抗葡萄球菌α-毒素抗体可与葡萄球菌α-毒素发生特异性反应,但不与葡萄球菌肠毒素A、霍乱毒素或假单胞菌外毒素A反应。
葡萄球菌α-毒素是一种33kD的水溶性单一多肽,是金黄色葡萄菌分泌的细胞毒性物质。这种蛋白具有膜损伤属性,可导致红细胞溶解。因此,它也被称为致死性溶血毒素或α-溶血素。葡萄球菌-毒素抗体可用于毒素-膜相互作用的研究。兔抗葡萄球菌α-毒素抗体可与葡萄球菌α-毒素发生特异性反应,但不与葡萄球菌肠毒素A、霍乱毒素或假单胞菌外毒素A反应。

免疫原

α-毒素(α-溶血素)来自 金黄色葡萄球菌

应用

成功使用该抗体的应用以及相关的同行评审论文如下。
酶联免疫吸附试验(1篇)
葡萄球菌α-毒素抗体可用于间接ELISA(1:50,000) 和斑点印迹免疫分析 (1:20,000)。

质量

抗血清经过处理以除去脂蛋白。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

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Shi-Jie Wan et al.
Frontiers in chemistry, 10, 877469-877469 (2022-04-19)
The emergence of antibiotic resistance in Staphylococcus aureus has necessitated the development of innovative anti-infective agents acting on novel targets. Alpha-hemolysin (Hla), a key virulence factor of S. aureus, is known to cause various cell damage and death. In this
Olivia A Todd et al.
mBio, 10(3) (2019-06-06)
Candida albicans and Staphylococcus aureus are among the most prevalent nosocomial pathogens that are responsible for severe morbidity and mortality, even with appropriate treatment. Using a murine model of polymicrobial intra-abdominal infection (IAI), we have previously shown that coinfection with
S Forti et al.
European journal of biochemistry, 181(3), 767-773 (1989-05-15)
alpha-Toxin, a lethal hemolytic toxin secreted by Staphylococcus aureus, forms ionic channels of large size in lipid membranes. To investigate the mechanism of channel assembly we have studied the kinetics of pore formation on small unilamellar vesicles. We have used
Alicia Lacoma et al.
Toxins, 13(2) (2021-02-11)
Staphylococcus aureus is a commensal and frequent colonizer of the upper respiratory tract. When mechanical ventilation disrupts natural defenses, S. aureus is frequently isolated from the lower airways, but distinguishing between colonization and infection is difficult. The objectives of this
María Belén Mestre et al.
Autophagy, 6(1), 110-125 (2010-01-30)
Staphylococcus aureus is a pathogen that causes serious infectious diseases eventually leading to septic and toxic shock. Classically S. aureus has been considered an extracellular pathogen, but cumulative evidence indicates that it invades cells and replicates intracellularly leading to staphylococcal

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