推荐产品
产品线
BioUltra
质量水平
方案
≥97% (SDS-PAGE)
表单
lyophilized powder
比活
≥4,500 units/mg protein
分子量
32.5 kDa
组成
Protein, ≥95% biuret
相关疾病
arthritis
储存温度
−20°C
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相关类别
一般描述
Research area: Cell signaling. Superoxide Dismutase (SOD) is found in allaerobic cells of the animals, plants, and microorganisms. It is a low molecularweight protein that exists as three different forms such as manganese SOD,copper–zinc SOD, and extracellular SOD.
应用
来自牛红细胞的超氧化物歧化酶已用于评估佐剂诱导的关节炎的活性参数的研究中。 来自牛红细胞的超氧化物歧化酶也已用于一项研究中,以简化在10-羧基癸基琼脂糖凝胶上使用电荷控制的疏水色谱法纯化超氧化物歧化酶的过程。
生化/生理作用
牛红细胞来源的超氧化物歧化酶可催化超氧化物自由基歧化为过氧化氢和分子氧。作为一种抗氧化剂,它在保护细胞免受氧自由基毒性作用方面起着至关重要的作用。与一氧化氮(NO)竞争超氧化物阴离子(可与NO反应生成过亚硝酸盐),因此SOD能促进NO的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中,SOD也表现出抑制细胞凋亡的作用。
单位定义
在pH 7.8,25℃条件下,3.0mL反应体积中,一个单位可在黄嘌呤氧化酶的偶联系统中抑制细胞色素c的减少达到50%。黄嘌呤氧化酶浓度应每分钟产生 0.025±0.005 的初始 ΔA550 。
警示用语:
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
从最新的版本中选择一种:
分析证书(COA)
Archives of medical research, 30(2), 132-137 (1999-06-18)
The purpose of this work was to evaluate the effect of superoxide dismutase (SOD) on primary swelling, lipoperoxidation, body thymus, and spleen weight in the adjuvant-induced arthritis (AIA) model in rats. Orally and intraperitoneally administered SOD (100 U/kg) from bovine
Frontiers in chemistry, 9, 614595-614595 (2021-02-27)
Native mass spectrometry has emerged as a powerful tool for structural biology as it enables the evaluation of molecules as they occur in their physiological conditions. Ion mobility spectrometry-mass spectrometry (IMS-MS) has shown essential in these analyses as it allows
Purification of pro- and eukaryotic superoxide dismutases by charge-controlled hydrophobic chromatography
Journal of Chromatography A, 590, 247-253 (1992)
Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice
Exploration of targeted anti-tumor therapy, 5, 416-433 (2024)
Characterisation by EPR spectroscopy of the co-ordination environment of copper in superoxide dismutase from horseradish (Armoracia rusticana Gaertn.)
Proceedings of the Royal Society of Edinburgh. Section B: Biology, 102, 273-277 (1994)
实验方案
Enzymatic Assay of Superoxide Dismutase
在测定超氧化物歧化酶活性时,使用了一种在550 nm处的连续分光光度法进行测定。一个酶单位可将酶偶联系统的细胞色素c还原率抑制50%。
Separation of Superoxide dismutase
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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