产品名称
莽草酸, ≥99%
Quality Level
assay
≥99%
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
mp
185-187 °C (lit.)
SMILES string
O[C@@H]1CC(=C[C@@H](O)[C@H]1O)C(O)=O
InChI
1S/C7H10O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1,4-6,8-10H,2H2,(H,11,12)/t4-,5-,6-/m1/s1
InChI key
JXOHGGNKMLTUBP-HSUXUTPPSA-N
Application
莽草酸已被用作定量测定根部顶端部分莽草酸含量的标准品。它还被用作莽草酸激酶测定的底物。
Biochem/physiol Actions
给药后在大鼠模型中观察到莽草酸具有致癌性。它可用作微生物中芳香族氨基酸、生物碱和其他芳香族代谢物的生物合成的前体。现已确知莽草酸可以抑制二磷酸腺苷(ADP)诱导的兔血小板聚集和血液凝固。
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Efficient elimination of nonstoichiometric enzyme inhibitors from HTS hit lists.
Habig M
Journal of Biomolecular Screening, 14(6), 679-689 (2009)
Varun Rawat et al.
Organic & biomolecular chemistry, 10(20), 3988-3990 (2012-04-24)
A new enantioselective synthesis of the anti-influenza agent (-)-oseltamivir free base (7.1% overall yield; 98% ee) and (-)-methyl 3-epi-shikimate (16% overall yield; 98% ee) has been described from readily available raw materials. Sharpless asymmetric epoxidation and diastereoselective Barbier allylation of
Inhibitory effects of shikimic acid on platelet aggragation and blood coagulation.
Ma Yi
Acta Pharmaceutica Sinica. B, 35, 1-3 (2000)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S5375-5G | 04061836946364 |
| S5375-1G | 04061836946333 |
| S5375-10MG | 04061836946272 |
