葡萄球菌肠毒素B 来源于金黄色葡萄球菌

与 MHC II 类分子和 T 细胞受体（TCR）的特异性 Vβ 区结合的葡萄球菌肠毒素 B（SEB），可导致单核细胞/巨噬细胞和 T 淋巴细胞的激活，可用作超抗原和免疫系统激活剂。 SEB 可用作 SEB 检测系统开发中的参考材料。

T 淋巴细胞的超抗原。 与主要组织相容性复合体（MHC）抗原和 CD28 结合的免疫系统激活剂。

包装尺寸基于蛋白质含量。

Staphylococcal Enterotoxin B (SEB) is a potent exotoxin produced by Staphylococcus aureus, classified as a superantigen due to its unique ability to activate T-cells non-specifically. This activation occurs through the cross-linking of T-cell receptors (TCRs) and major histocompatibility complex (MHC) class II molecules, leading to a massive release of cytokines and an exaggerated immune response. SEB is associated with food poisoning and toxic shock syndrome, making it a critical agent for studying the mechanisms of bacterial pathogenesis and immune dysregulation.
In addition to its role in infectious disease research, SEB serves as a valuable tool for investigating autoimmune conditions and the development of immunotherapies. Its ability to induce T-cell activation and proliferation makes it an important reagent for exploring T-cell biology, including differentiation, memory formation, and the effects of various immunomodulators.