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Merck
CN

S4881

Sigma-Aldrich

葡萄球菌肠毒素B 来源于金黄色葡萄球菌

别名:

SEB, 肠毒素B,葡萄球菌

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.25

包含

sodium phosphate buffer as balance

质量水平

组成

Protein, ~25% Lowry

存货情况

not available in USA

杂质

Staphylococcal enterotoxin A (SEA), essentially free

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

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应用

与 MHC II 类分子和 T 细胞受体(TCR)的特异性 Vβ 区结合的葡萄球菌肠毒素 B(SEB),可导致单核细胞/巨噬细胞和 T 淋巴细胞的激活,可用作超抗原和免疫系统激活剂。 SEB 可用作 SEB 检测系统开发中的参考材料。

生化/生理作用

T 淋巴细胞的超抗原。 与主要组织相容性复合体(MHC)抗原和 CD28 结合的免疫系统激活剂。

包装

包装尺寸基于蛋白质含量。

相关产品

产品编号
说明
价格

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

高风险级别生物产品--毒素类产品

分析证书(COA)

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Oliver G Weingart et al.
Sensors (Basel, Switzerland), 12(2), 2324-2339 (2012-03-23)
Prevalent incidents support the notion that toxins, produced by bacteria, fungi, plants or animals are increasingly responsible for food poisoning or intoxication. Owing to their high toxicity some toxins are also regarded as potential biological warfare agents. Accordingly, control, detection
Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Iria Gomez-Tourino et al.
Nature communications, 8(1), 1792-1792 (2017-11-28)
Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10

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