S4447
α-Synuclein E46K 人
recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder
别名:
NACP (Non-a-beta component of Alzheimer disease amyloid, precursor), PARK1, PARK4, PD1, non A4 component of amyloid precursor
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About This Item
UNSPSC代码:
12352200
NACRES:
NA.32
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重组
expressed in E. coli
质量水平
方案
≥90% (SDS-PAGE)
表单
lyophilized powder
分子量
apparent mol wt 19-20 kDa
UniProt登记号
相容性
for use with ABI StepOnePlus
运输
dry ice
储存温度
−20°C
基因信息
human ... SNCA(6622)
生化/生理作用
Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A transition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein.
Deposition of α-synuclein as fibrillary tangles is a hallmark of certain neurodegenerative diseases including Parkinson′s. Among the familial mutations of α-synuclein, E46K has the greatest potential to aggregate.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
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