所有图片(3)
别名:
磺基罗丹明101磺酰氯
经验公式（希尔记法）:
C31H29ClN2O6S2
CAS号:
分子量:
625.15
Beilstein:
8667894
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
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形式
powder
组成
Dye content, ~75%
杂质
~1 mol/mol chloroform as solvent of crystallization
溶解性
methanol: 10 mg/mL
荧光
λex 586 nm; λem 605 nm in H2O
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O
InChI
1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2
InChI key
MPLHNVLQVRSVEE-UHFFFAOYSA-N
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一般描述
磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。该染料可专门用作新皮质中星形胶质细胞的标记。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。
应用
酸性桃红 101 酰氯已被用于封装的荧光探针中，作为模型药物研究基于鼠李糖半乳糖醛酸-I 的微胶囊的药物递送特性。它还作为星形胶质细胞特异性染料，用于共聚焦成像。
联系
酸性桃红 101 的两种单磺酰氯衍生物的混合物。
警示用语：
Danger
危险分类
Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
易制毒化学品（2类）
In vivo imaging of oligodendrocytes with sulforhodamine 101
Robert A Hill
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Loop diuretics such as bumetanide and furosemide enhance aminoglycoside ototoxicity when co-administered to patients and animal models. The underlying mechanism(s) is poorly understood. We investigated the effect of these diuretics on cellular uptake of aminoglycosides, using Texas Red-tagged gentamicin (GTTR)
Yang Liu et al.
Pharmaceutical research, 29(12), 3273-3277 (2012-07-19)
The biodistribution of Lipid/Calcium/Phosphate (LCP) nanoparticles (NPs) in tumor-bearing mice was investigated using fluorescence imaging. A quantitative validation of this method was done by (3)H and (111)In labeling of the nanoparticles. The biodistribution of LCP NPs containing oligonucleotides was investigated
Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release
Anna J
PLoS ONE, 11(12), e0168050-e0168050 (2016)
Ping-Jung Su et al.
Biomacromolecules, 13(9), 2917-2925 (2012-08-11)
To understand complex micro/nanoscale ECM stem cell interactions, reproducible in vitro models are needed that can strictly recapitulate the relative content and spatial arrangement of native tissue. Additionally, whole ECM proteins are required to most accurately reflect native binding dynamics.
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