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Merck
CN

S3386

Sigma-Aldrich

山梨糖醇酐倍半油酸酯

nonionic surfactant

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别名:
Arlacel® 83, Span® 83
CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25

生物来源

corn

质量水平

蒸汽压

0.81 psi ( 20 °C)

形式

liquid

折射率

n20/D 1.478 (lit.)

密度

0.989 g/mL at 25 °C (lit.)

官能团

ester

脂质类型

oils

运输

ambient

储存温度

room temp

SMILES字符串

OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

InChI key

SPFRYHCSFBFNTR-RKGWDQTMSA-N

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一般描述

倍半油酸山梨坦(SSO) 是一种山梨醇衍生物乳化剂。它是外用皮质类固醇、外用抗生素、外用抗真菌剂、保湿霜和乳液以及外用维A酸中的常见乳化剂成分。

生化/生理作用

倍半油酸山梨坦在生产球形丙烯酰胺微珠的聚合过程中可用作稳定剂。它已被用于许多外用药物。 最近发现SSO与过敏性皮炎有关。

其他说明

脂肪酸组成:油酸(C18:1)约70%;主要用于平衡的棕榈酸(C16:0)、硬脂酸(C18:0)和亚油酸(C18:2)。

法律信息

Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Adam Asarch et al.
Dermatitis : contact, atopic, occupational, drug, 19(6), 323-327 (2009-01-13)
In the past, sorbitan sesquioleate (SSO) was reported as an uncommon allergen, but recent data suggest SSO may be an important sensitizer. To present data on 13 of 112 dermatitis patients who reacted to SSO and/or sorbitan monooleate (SMO) on
Allergic contact dermatitis to sorbitan sesquioleate in Adaptic wound dressing.
F B de Waard-van der Spek et al.
Contact dermatitis, 57(1), 54-56 (2007-06-20)
Y H Lin et al.
Journal of microencapsulation, 17(1), 1-11 (2000-02-12)
Microencapsulation of 5-fluorouracil was successfully accomplished with poly(ortho ester) polymers by the emulsification-solvent evaporation method. While actual drug loading increased with increasing drug load (5-15% w/w), the entrapment efficiency remained essentially unaffected, under a given set of experimental conditions. Incorporation
Contact dermatitis due to emulsifiers.
F Pereira et al.
Contact dermatitis, 36(2), 114-114 (1997-02-01)
M Iwata et al.
Journal of microencapsulation, 16(1), 49-58 (1999-02-11)
PLGA multiphase microspheres were prepared by the multiple emulsion solvent evaporation method using acetonitrile as the polymer solvent and mineral oil as the evaporation medium. The preparation process was further developed in the present study to reduce the particle size

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