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Merck
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主要文件

安全信息

S3072

Sigma-Aldrich

Spiramycin adipate

别名:

Spiramycin hexanedioate

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About This Item

EC 号:
MDL编号:
UNSPSC代码:
51101500

表单

powder

效能

3948 I.U. per mg

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

颜色

off-white

抗生素抗菌谱

Gram-positive bacteria

作用机制

protein synthesis | interferes

储存温度

2-8°C

一般描述

Chemical structure: macrolide

应用

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

生化/生理作用

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

其他说明

This product is a mixture of spiramycins I, II, and III.
Keep container tightly closed in a dry and well-ventilated place.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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O Rolin et al.
Pathologie-biologie, 34(5), 476-478 (1986-05-01)
Experimental septicemia was induced in mice by intraperitoneal injection of 10 to 100 lethal doses of Staphylococcus aureus and Streptococcus pneumoniae. Animals were treated by a mixture of adipic acid and spiramycin (subcutaneous route) or by spiramycin base (oral route)
Acute bronchopulmonary infections: treatment with i.v. spiramycin.
F Vachon and S Kernbaum
Chemotherapia, 6, 282-285 (1987)

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